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The Essential Patient’s IVF Preparation Checklist [XLS Download]

Feb 27, 2025

IVF preparation involves a complex mix of emotional, physical, and logistical steps. It can quickly become daunting when you’re busy coordinating assessments, appointments, and anxieties alongside the responsibilities and commitments of everyday life. 

Schedules and spreadsheets might sound boring, but staying on top of what’s going on throughout the IVF experience is essential. A well-planned IVF preparation checklist can take the guesswork out of the process and ensure you don’t feel overwhelmed or accidentally overlook important details. 

Table of contents

  1. Pre-IVF preparation
  2. The medication phase
  3. Egg retrieval and fertilization
  4. Embryo transfer date and beyond
  5. The role of technology in IVF preparation and success

1. Pre-IVF preparation (3 months before)

Medical

On the medical side, a few screenings and tests are essential before you start your IVF journey. The clinic will guide you through the pre-treatment checklist, which is much less daunting than it may initially seem. You can expect to do:

  • Bloodwork: Blood tests check hormone levels (such as AMH, FSH, LH, and estradiol) to assess ovarian reserve (egg quantity and potential quality). They also evaluate thyroid function, screen for infectious diseases, and check for underlying conditions affecting fertility.
  • Ultrasounds: The clinic will perform transvaginal ultrasounds to assess the health of your uterus and endometrial lining and ensure the uterine environment is suitable for implantation.They will also examine your ovaries and follicles to evaluate ovarian reserve and monitor follicle development during stimulation.
  • Sperm tests: Also called a semen analysis, this test assesses factors that affect fertility, such as sperm count, morphology (shape), and volume (the amount of semen produced). 
  • STI tests: These tests screen for common Sexually Transmitted Infections (STIs) like syphilis and chlamydia, which can affect fertility. 

Pre-IVF medication preparation

Financial

Let’s face it: IVF isn’t exactly cheap. Financial planning is a vital step before taking the plunge with IVF. Although you might not want to, it’s a sensible idea to review your financial situation and the type of payment plan option you might need. 

Some countries, like the UK, for example, subsidize IVF treatment. In other cases, you could get financial support through your insurance coverage. Many clinics also offer treatment plans, allowing you to spread the costs over time. To make the best decision, it’s worth comparing prices and payment options across clinics to choose the most suitable path.

Lifestyle

Even minor tweaks to your lifestyle can boost your mental and physical health. While there are no ‘right’ or ‘wrong’ approaches to well-being, there are a few standard ‘don’ts,’ that are present in any IVF preparation checklist, such as quitting smoking and limiting alcohol consumption. 

The phrase ‘you are what you eat’ comes into play during your pre-IVF prep. Diet matters for sustaining energy levels, nutrient absorption, and immunity. Nutritionists and doctors recommend a Mediterranean-style plate, such as:

  • Plenty of leafy greens. 
  • Antioxidant-rich fruits and vegetables.
  • Fiber-filled whole grains. 
  • Probiotic foods for gut health. 

Another healthy habit is to pair a stable diet with consistent exercise. We’re not talking Ironman training—light activities such as walking and yoga will do the trick. 

Mindset

What’s happening up top is just as valuable as what’s happening in your body. Nowadays, counseling is very common and doesn’t carry the stigma that it once did. Counseling and other mental health therapies can help you, your partner, and your family prepare emotionally for the IVF process. 

Above all, it’s essential to keep your feet on the ground – metaphorically, of course. Setting realistic expectations helps you understand the potential successes and limitations of IVF. For example, success rates vary significantly depending on age and medical history. You might need multiple rounds of IVF to achieve pregnancy, and in some cases, you might not get pregnant in the end. No matter the rollercoaster, remember that the journey is uniquely yours. 


2. The medication phase (1-4 weeks before)

What to expect during the medication phase 

The goal of the medication phase is to help your ovaries produce eggs so the clinic can retrieve as many as possible for the IVF cycle(s). Here’s how it works: Follicles are tiny, fluid-filled sacs within your ovaries. Each one contains an immature egg; when the egg matures, the follicle ruptures and releases the egg. Medication supports the maturing and releasing of these eggs at the right moment. 

There’s no defined timeline for the medication phase, mainly because a lot of monitoring is involved, and every person’s body will respond differently. Your clinic will develop a personalized medication plan and continue to monitor your blood tests and follicle development.

Prescribed medications

You’ll begin hormone injections to stimulate your ovaries to produce more than one egg. You’ll also take medication to stop your ovaries from releasing the eggs (also called down-regulation). 

Remember that your medication requirements will vary from others’—the best bet is to listen to your doctor, as they’ll know exactly what you need. Don’t hesitate to contact your doctor if you have any questions about medications, side effects, administering injections, or anything else. 

Although the clinic will guide you, it is essential to take responsibility for your prescribed medications. Try pill organizers and alarms to help you stay on schedule, and download our IVF preparation checklist to track key information like dosage and frequency. 

Trigger shot 

The trigger shot is an injection that helps the eggs reach the final stage of maturity. Essentially, it ‘triggers’ the ovaries to release the mature eggs. You’ll receive it approximately 36 hours before the scheduled egg retrieval procedure. The timing has to be right to ensure the eggs are mature: your doctor will typically administer the trigger shot when the follicles (which contain the eggs) have reached an optimal size, usually around 18-20mm in diameter.

Finding a Fertility Clinic

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3. What to expect during egg retrieval and fertilization

What to expect during egg retrieval

Egg retrieval, or oocyte retrieval, is when mature eggs are collected from your ovaries. The procedure typically takes place in a fertility clinic or hospital and is performed under light sedation or anesthesia for your comfort. The procedure involves:

  • Sedation/Anesthesia: You will receive mild sedation or anesthesia, so you won’t feel pain during the retrieval.
  • Ultrasound Guidance: The fertility doctor will use a transvaginal ultrasound probe to visualize your ovaries.
  • Egg Collection: A fine needle is inserted through the vaginal wall to aspirate fluid from the follicles, retrieving the eggs in the process. The entire procedure usually takes about 20–30 minutes.

Shortly after the procedure, the clinic will discuss how many eggs they’ve collected. There’s no defined number – not every follicle contains an egg, and the number of eggs retrieved varies from person to person. 

It’s important to prepare yourself for the possibility that the clinic may not collect as many eggs as you hoped. Egg retrieval results can vary from person to person, and not every follicle will contain a mature egg. Typically, clinics collect between 5 to 15 eggs, depending on factors like age and ovarian reserve. 

If the number is lower than expected, your doctor will guide you on the next steps, whether that means adjusting your approach or considering additional cycles. Remember that it’s not just the quantity but the quality of the eggs that matters, so don’t get fixated on a number. 

How to prepare

  • Avoid eating or drinking anything for approximately seven hours before the egg retrieval. 
  • Have a bath or shower beforehand. 
  • Don’t wear any makeup, jewelry, or perfume. 

What to expect after egg retrieval

After the procedure, you may experience mild cramping, bloating, or spotting, which should subside within a day or two. Plan to rest for the remainder of the day and avoid strenuous activity. Your clinic will provide specific aftercare instructions, including when you can restart normal activities. If you experience severe pain or heavy bleeding, contact your doctor immediately.

Fertilization considerations

One of IVF’s excellent benefits is its flexibility on your journey to becoming a parent. Depending on your unique circumstances, you’ll have the option to proceed with donor eggs, sperm, or embryos, or even a gestational surrogate. It’s normal to have concerns or questions about topics like legal rights, anonymity, and identity. Take the opportunity to open up about this in counseling sessions or with your doctors and family. 

Your chosen fertilization method will influence the steps leading up to the embryo transfer, including how much contact you have with the clinic. 

 

4. Embryo transfer day and beyond

What to expect on the transfer day

Before the embryo transfer, the clinic selects the embryos through a process called embryo grading. Traditional embryo grading is carried out by an embryologist who reviews the embryos under a microscope to evaluate developmental factors like their structure, size, and cell development. 

Technologies like AI and computer vision are increasingly being adopted by clinics worldwide to not only speed up the process but also enhance accuracy and reduce human bias. For example, solutions like AIVF use advanced algorithms to analyze embryo images, evaluating factors such as cell morphology and developmental patterns with a level of precision that surpasses traditional grading methods. This allows for more objective selection, potentially improving the chances of successful implantation.

Once the embryo is selected, you move to the transfer stage. The embryo transfer process is relatively quick and painless; the fertility doctor will transfer the embryos using a thin catheter. 

How to prepare

  • Take time to relax the night before the embryo transferfeeling nervous is natural, but don’t let the jitters get the best of you!
  • Wear warm and loose-fitting clothing.
  • Take some entertainment, like books or music. 
  • Arrive with a full bladder. 

Aftercare and rest

Rest should be your top priority after the embryo transfer—this is the time to put yourself first. Your best bets are light exercise (think walking and stretching), healthy foods, and plenty of sleep

The two-week wait 

After the embryo transfer day, you’ll have to wait approximately two weeks before you can take a pregnancy test. You may start to see some new symptoms seven days after embryo transfer, such as cramping, fatigue, or bloating. 

Many patients find this two-week wait nerve-wracking, but it’s essential to stay cool, calm, and collected—and avoid the temptation to take the pregnancy test too early. Keep investing time in the positive habits you adopted right at the beginning of your IVF journey: mindfulness, light exercise, and healthy eating. 

HCG Trigger shot side effects

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The role of technology in IVF preparation and success

The IVF process can feel confusing, especially when you’re not familiar with medical language and technical jargon. The right tools and preparation can help these unchartered waters feel more familiar, starting with embryo selection.

Solutions like AIVF give you greater visibility over what’s going on at the critical embryo grading stage. AIVF uses innovative scoring technology powered by AI-driven algorithms to provide highly accurate information about each embryo. Sounds too techy? Our EMA platform includes an easy-to-use interface for clinics and patients, helping you understand what the scoring means for your chances of a successful pregnancy. 

With AIVF’s transparent and non-invasive embryo scoring technology, you can feel confident that you’re doing everything possible to improve embryo selection and reduce the number of cycles needed to meet your bouncing baby. 

Ready to feel organized, confident, and prepared for your IVF journey? Download our preparation checklist to help you get started.